Novel alkoxybenzamide inhibitors of poly(ADP-ribose) polymeraseMENEAR, Keith A; ADCOCK, Claire; FENANDEZ LENCE, Carlos et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 14, pp 3942-3945, issn 0960-894X, 4 p.Article

Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth byAZD2281 and CisplatinEVERS, Bastiaan; DROST, Rinske; SMITH, Graeme C. M et al.Clinical cancer research. 2008, Vol 14, Num 12, pp 3916-3925, issn 1078-0432, 10 p.Article

Identification and optimisation of novel and selective small molecular weight kinase inhibitors of mTORMENEAR, Keith A; GOMEZ, Sylvie; SEBASTIAN, Luisa et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 20, pp 5898-5901, issn 0960-894X, 4 p.Article

Poly(ADP-Ribose) Polymerase-1 Inhibitor Treatment Regresses Autochthonous Brca2/p53-Mutant Mammary Tumors In vivo and Delays Tumor Relapse in Combination with CarboplatinHAY, Trevor; MATTHEW, James R; CLARKE, Alan R et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 9, pp 3850-3855, issn 0008-5472, 6 p.Article

4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one : A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1MENEAR, Keith A; ADCOCK, Claire; JAVAID, Hashim et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 20, pp 6581-6591, issn 0022-2623, 11 p.Article

Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATMHICKSON, Ian; YAN ZHAO; RICHARDSON, Caroline J et al.Cancer research (Baltimore). 2004, Vol 64, Num 24, pp 9152-9159, issn 0008-5472, 8 p.Article

Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinaseHOLLICK, Jonathan J; RIGOREAU, Laurent J. M; HUMMERSONE, Marc G et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 8, pp 1958-1972, issn 0022-2623, 15 p.Article

Phthalazinones. Part 1: The design and synthesis of a novel series of potent inhibitors of poly(ADP-ribose)polymeraseLOH, Vincent M; COCKCROFT, Xiao-Ling; MENEAR, Keith A et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 9, pp 2235-2238, issn 0960-894X, 4 p.Article

Phthalazinones 2 : Optimisation and synthesis of novel potent inhibitors of poly(ADP-ribose)polymeraseCOCKCROFT, Xiao-Ling; DILLON, Krystyna J; DIXON, Lesley et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 4, pp 1040-1044, issn 0960-894X, 5 p.Article

Efficient deletion of normal Brca2-deficient intestinal epithelium by poly(ADP-ribose) polymerase inhibition models potential prophylactic therapyHAY, Trevor; JENKINS, Helen; SANSOM, Owen J et al.Cancer research (Baltimore). 2005, Vol 65, Num 22, pp 10145-10148, issn 0008-5472, 4 p.Article